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Estimating utility scores in young children with acute rotavirus gastroenteritis in the UK

Alan Martin1, Suzanne Cottrell, Baudouin Standaert

  • 1GlaxoSmithKline Ltd, Stockley Park, Middlesex, UK.

Journal of Medical Economics
|May 20, 2009
PubMed

Insights

Acute rotavirus gastroenteritis significantly impacts children under 5, reducing their quality of life. This study quantifies these health impacts for economic evaluations.

Area of Science:

  • Health Economics
  • Pediatrics
  • Public Health

Background:

  • Rotavirus gastroenteritis is a significant cause of illness in young children globally.
  • Understanding the quality of life impact is crucial for resource allocation in healthcare.

Purpose of the Study:

  • To estimate utility scores for varying severities of acute rotavirus gastroenteritis in UK children under 5.
  • To provide quantitative data for economic evaluations of rotavirus interventions.

Main Methods:

  • UK general practitioners and paediatricians assessed health states using the EuroQol (EQ-5D) questionnaire.
  • Scores were adjusted for self-care and mobility limitations and converted to utility values.

Main Results:

  • Mean utility scores varied significantly by disease severity and care setting (primary vs. hospital).
  • General practitioners rated primary care cases with utilities ranging from 0.781 to 0.688.
  • Paediatricians rated hospitalised severe/very severe cases with utilities from 0.595 down to 0.077.

Conclusions:

  • Acute rotavirus gastroenteritis substantially diminishes quality of life in young children.
  • The study provides valuable utility estimates for economic analyses of rotavirus disease burden and prevention.
Abstract

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