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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Published on: June 6, 2025

Clinical outcome of hypertension management

Vivian Wy Lee1, Tony Hw Chan, Tina Tl Ko

  • 1School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong. vivianlee@cuhk.edu.hk

Journal of Medical Economics
|May 20, 2009
PubMed

Insights

Uncontrolled hypertension in Hong Kong Chinese patients significantly increases cardiovascular events (CVEs) and medication use. Poorly managed blood pressure also leads to higher hospitalization costs, highlighting the need for better hypertension control.

Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Background:

  • Hypertension management is crucial for preventing cardiovascular events (CVEs).
  • Understanding medication use patterns in hypertensive patients is essential for optimizing treatment.
  • The economic burden of inadequately controlled hypertension requires investigation.

Purpose of the Study:

  • To examine the link between uncontrolled hypertension, medication patterns, and CVE incidence over five years.
  • To estimate the hospitalization costs associated with inadequately controlled hypertension.

Main Methods:

  • Retrospective observational study of 210 hypertensive patients from 2001-2005.
  • Primary endpoints: blood pressure deviation from treatment goals (extent, duration, prevalence).
  • Secondary endpoints: CVE incidence and hospitalization days for uncontrolled hypertension.

Main Results:

  • Inadequately controlled systolic and diastolic blood pressure correlated with increased CVE incidence and polypharmacy (cardiovascular, non-cardiovascular, and total drug usage).
  • Patients with persistently uncontrolled blood pressure showed a higher incidence of CVEs.
  • Mean hospitalization cost due to CVEs was HK$42,584.0, representing 3.3% of total healthcare expenditure in 2005.

Conclusions:

  • Inadequately controlled blood pressure is linked to a higher incidence of cardiovascular events and polypharmacy in Hong Kong Chinese hypertensive patients.
  • Effective hypertension management is critical to reduce CVEs and associated healthcare costs.
Abstract

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