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Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Diabetes: glycaemic control in type 2.

Bala Srinivasan¹, Nick Taub, Kamlesh Khunti

¹Department of Diabetes and Endocrinology, University Hospitals of Leicester NHS Trust, Leicester, UK.

BMJ Clinical Evidence

|May 20, 2009

Summary

This systematic review evaluates interventions for type 2 diabetes, a progressive glucose metabolism disorder. It found 69 studies on treatments like metformin, insulin, and diet, assessing their effectiveness and safety.

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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

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Improving IV Insulin Administration in a Community Hospital

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A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

Area of Science:

Endocrinology
Metabolic Disorders
Clinical Research

Background:

Type 2 diabetes affects 5% of the global population, often linked with metabolic syndrome, obesity, hypertension, and dyslipidemia.
Progressive hyperglycemia in type 2 diabetes leads to microvascular and macrovascular complications.
Cardiovascular disease (CVD) is a significant risk associated with type 2 diabetes and metabolic syndrome.

Purpose of the Study:

To systematically review the effects of various interventions in adults diagnosed with type 2 diabetes.
To assess the effectiveness and safety of different treatment modalities for managing type 2 diabetes.

Main Methods:

Systematic review methodology was employed, searching major databases including Medline, Embase, and The Cochrane Library up to October 2006.
Inclusion criteria encompassed systematic reviews, randomized controlled trials (RCTs), and observational studies.
Harms alerts from regulatory agencies like the FDA and MHRA were also incorporated.

Main Results:

A total of 69 studies met the inclusion criteria for the systematic review.
The quality of evidence for interventions was evaluated using the GRADE (Grading of Recommendations Assessment, Development and Evidence) system.
Data from these studies informed the assessment of intervention effectiveness and safety.

Conclusions:

The review presents findings on the effectiveness and safety of numerous interventions for type 2 diabetes.
Interventions evaluated include combined oral drug treatments, diet, education, various insulin regimens, intensive treatment programs, meglitinides, metformin, monotherapy, and sulfonylureas.
Blood glucose self-monitoring at different frequencies was also assessed as an intervention.