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Nocturnal enuresis

Darcie Kiddoo1

  • 1University of Alberta, Alberta, Canada.

BMJ Clinical Evidence
|May 20, 2009
PubMed

Insights

This systematic review examines treatments for nocturnal enuresis (bedwetting). It found various interventions, including alarms and medications, with varying effectiveness and safety profiles for children and adults.

Area of Science:

  • Pediatric Urology
  • Sleep Medicine
  • Evidence-Based Medicine

Background:

  • Nocturnal enuresis impacts a significant percentage of children and adults, with spontaneous resolution rates of 15% annually.
  • Treatment is generally not recommended for children under 5 and may be inappropriate for those under 7.

Purpose of the Study:

  • To systematically review the effectiveness and safety of interventions for nocturnal enuresis symptoms.

Main Methods:

  • A comprehensive search of major medical databases (Medline, Embase, Cochrane Library) up to March 2007 was conducted.
  • Included systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • GRADE evaluation assessed the quality of evidence for interventions.

Main Results:

  • Fourteen relevant studies met the inclusion criteria.
  • The review evaluated a range of interventions, including acupuncture, anticholinergics, desmopressin, dry bed training, enuresis alarms, hypnotherapy, and tricyclic antidepressants.

Conclusions:

  • The review provides information on the effectiveness and safety of multiple nocturnal enuresis treatments.
  • Interventions assessed include both behavioral (e.g., alarms, dry bed training) and pharmacological (e.g., anticholinergics, desmopressin, tricyclics) approaches.
Abstract

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