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Related Experiment Video

Updated: Jun 23, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Nonneurogenic voiding disorders: what's new?

Kenneth I Glassberg¹, Andrew J Combs

¹Division of Pediatric Urology, Morgan Stanley Children's Hospital of New York-Presbyterian, New York NY 10032, USA. Kglassberg@aol.com

Current Opinion in Urology

|May 20, 2009

Summary

Pediatric nonneurogenic voiding disorders (NNVDs) are better understood through symptom diagnosis and urodynamics. While some therapies show promise, newer treatments for overactive bladder in children require further investigation.

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Area of Science:

Pediatric Urology
Voiding Dysfunction
Urodynamics

Background:

Nonneurogenic voiding disorders (NNVDs) in children are increasingly recognized.
Urodynamic testing and therapeutic options for NNVDs are evolving.
This review addresses recent advancements in the diagnosis and management of pediatric voiding disorders.

Purpose of the Study:

To review current literature on pediatric nonneurogenic voiding disorders.
To highlight advancements in diagnosis, urodynamic testing, and treatment options.
To synthesize recent findings and their implications for clinical practice.

Main Methods:

Review of recent studies on pediatric nonneurogenic voiding disorders.
Analysis of diagnostic approaches, including symptomatology and urodynamic findings.
Evaluation of treatment efficacy for various voiding dysfunctions and enuresis.

Main Results:

Diagnosis of NNVDs correlates with urodynamic findings and treatment outcomes.
Bowel and behavioral disorders are associated with NNVDs and impact treatment response.
Efficacy of symptom-directed therapies, biofeedback, Botox, and anticholinergics for overactive bladder and enuresis were assessed.
Uroflowmetry alone is insufficient for predicting voiding disorders; test parameters have minimal impact.

Conclusions:

Predicting voiding disorders solely on uroflowmetry is inaccurate.
Behavioral disorders do not prevent successful treatment of NNVDs.
Newer therapies like Botox and expanded use of anticholinergics for pediatric overactive bladder warrant further scrutiny.