Related Experiment Video

Updated: Jun 23, 2026

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing
08:05

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

A retrospective six-year national survey of P. multocida infections in Israel

William Nseir1, M Giladi, I Moroz

  • 1Holy Family Hospital, Nazareth, Israel. w.nseir@yahoo.com

Scandinavian Journal of Infectious Diseases
|May 20, 2009
PubMed

Insights

Pasteurella multocida infections from pet bites are common. While most cases have a good prognosis, elderly patients with comorbidities and bacteremia face higher risks, often requiring surgery.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Pasteurella multocida is frequently implicated in pet-associated bite infections.
  • Previous reports often highlight severe outcomes, potentially skewing the perception of infection severity.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of Pasteurella multocida infections.
  • To determine the incidence and risk factors associated with P. multocida infections in a large population.

Main Methods:

  • A retrospective survey of P. multocida infections was conducted in Israeli hospitals between 2000 and 2005.
  • Data were collected from patient charts identified through clinical microbiology records.

Main Results:

  • 77 cases of P. multocida infection were identified, with an annual incidence of 0.19/100,000.
  • The mortality rate was 2.6%, primarily affecting elderly patients (>65 years) with comorbidities (diabetes, cirrhosis) and bacteremia.
  • Cats were the source of infection in 54% of cases; 53.7% required surgical debridement, with some needing reoperations.

Conclusions:

  • Hospitalized patients with P. multocida infections generally have a favorable prognosis.
  • Elderly patients, those with bacteremia, and individuals with comorbidities represent a higher-risk group.
  • Surgical intervention and potential reoperations are common management strategies for P. multocida infections.

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...