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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Factors to predict recurrence of atrial fibrillation in patients with hypertension
Xiaojing Ma1, XingHua Zhang, WenBin Guo
1Department of Cardiology, Provincial Hospital affiliated to Shandong University, Jinan, P.R. China;
Insights
Patients with hypertension experiencing atrial fibrillation (AF) recurrence can be identified. Key predictors include increased P-wave dispersion, P-LAA time, and left atrial appendage dysfunction.
Area of Science:
- Cardiology
- Hypertension Research
- Electrophysiology
Background:
- Essential hypertension is linked to higher atrial fibrillation (AF) recurrence rates post-conversion.
- Predicting AF recurrence in hypertensive patients is crucial for management.
Purpose of the Study:
- To identify parameters predicting AF recurrence in patients with essential hypertension.
- To evaluate the role of echocardiographic and electrocardiographic measures.
Main Methods:
- Retrospective analysis of 136 hypertensive patients with AF history.
- Measurement of P-wave duration/dispersion, left atrium (LA) and left atrial appendage (LAA) size/function.
- Assessment of P-wave to LAA ejection flow time (P-LAA).
Main Results:
- 38.2% experienced AF recurrence.
- Higher P-LAA, P-wave dispersion, LA diameter, and LAA volumes in recurrent AF group.
- Lower LAA ejection fraction (EF-LAA) and peak emptying velocity in recurrent AF group.
Conclusions:
- Increased P-wave dispersion, prolonged P-LAA, dilated LA, and impaired LAA function predict AF recurrence in hypertensive patients.
- These parameters aid in identifying high-risk individuals for targeted interventions.
Background:
Patients with essential hypertension had a higher recurrence rate of atrial fibrillation (AF) than patients without hypertension. This study evaluated the role of various parameters for predicting recurrence after conversion of AF in patients with essential hypertension.
Methods:
We retrospectively analyzed 136 patients with essential hypertension and a known history of AF. P-wave duration and dispersion were measured in a 12-lead electrocardiograph. The size and function of the left atrium (LA) and left atrial appendage (LAA) were assessed by transthoracic and transesophageal echocardiography. The time interval from initiation of P-wave to the start of LAA ejection flow (P-LAA) was measured at the same time. All the patients were followed up for a period of 12 +/- 6 months for the recurrence of AF.
Results:
In the follow-up period, 38.2%of patients underwent AF recurrence. Age, P-LAA, P(max), P-wave dispersion, left atrium diameter (LAD), and maximum and minimum LAA volume were significantly higher in patients with AF recurrence than in patients without AF recurrence, while EF-LAA and LAA peak emptying velocity were much lower in patients with AF recurrence. P-LAA had positive correlation with LAD and P-wave dispersion (r = 0.501, p < 0.0001; r = 0.713, p < 0.0001).
Conclusion:
These results indicated that increased P-wave dispersion, P-LAA in addition to the dilated LA, and the depressed LAA function may be useful to identify patients with hypertension at risk of recurrent AF.
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