Related Experiment Video

Updated: Jun 23, 2026

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
08:20

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

GARP: a key receptor controlling FOXP3 in human regulatory T cells

M Probst-Kepper1, R Geffers, A Kröger

  • 1Junior Research Group for Xenotransplantation, Department of Visceral and Transplant Surgery, Hannover Medical School, Hannover, Germany.

Journal of Cellular and Molecular Medicine
|May 21, 2009
PubMed
Summary

Researchers identified GARP as a key regulator of FOXP3 in T(reg) cells. This discovery, involving LGALS3 and LGMN, offers potential for therapeutic manipulation of T cells in human diseases.

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