[Moyamoya disease in childhood]

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Updated: Aug 11, 2026

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry
06:53

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry

Published on: November 23, 2011

I Velkey1, B Lombay

  • 1Borsod-Abaúj-Zemplén Megyei Kórház-Rendelöintézet, Miskolc.

Orvosi Hetilap
|October 13, 1991
PubMed

Insights

Moyamoya disease, a rare cerebrovascular disorder, was observed in two children presenting with transient ischemic attacks. Hyperventilation was noted to provoke symptoms, highlighting its significance in this condition.

Area of Science:

  • Neurology
  • Cerebrovascular Diseases
  • Pediatric Neurology

Background:

  • Moyamoya disease is a rare, progressive cerebrovascular condition.
  • It involves stenosis of the circle of Willis and compensatory vascular networks.
  • This disorder primarily affects children and young adults.

Observation:

  • Two pediatric cases of moyamoya disease are presented.
  • Both patients experienced transient ischemic attacks (TIAs).
  • Hyperventilation was identified as a key factor in provoking TIAs.

Findings:

  • The study details the clinical presentation and diagnostic challenges of moyamoya disease.
  • It emphasizes the role of hyperventilation in symptom exacerbation.
  • This report marks the first documented instance of moyamoya disease in Hungary.

Implications:

  • Increased awareness of moyamoya disease in pediatric populations is crucial.
  • Recognizing hyperventilation's role can aid in early diagnosis and management.
  • This case series contributes to understanding moyamoya disease prevalence and characteristics globally.

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