IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

Jian-Bin Wang1, Robert Sonn, Yemmsrach K Tekletsadik

  • 1Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.

Summary

IQGAP1 regulates cell proliferation by coordinating cell growth and division via a novel CDC42-mTOR pathway. Phosphorylation and CDC42 binding are crucial for IQGAP1

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