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Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility

Alicia Beeghly-Fadiel1, Wei Lu, Ji-Rong Long

  • 1Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203-1738, USA.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
|May 21, 2009
PubMed
Summary

Genetic variations in the matrix metalloproteinase-2 (MMP-2) gene are linked to breast cancer risk. Specific MMP-2 promoter polymorphisms show a reduced risk, suggesting a role in breast cancer susceptibility.

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