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Related Concept Videos

Elastic Strain Energy for Shearing Stresses01:20

Elastic Strain Energy for Shearing Stresses

As discussed in previous lessons, strain energy in a material is the energy stored when it is elastically deformed, a concept crucial in materials science and mechanical engineering. This energy results from the internal work done against the cohesive forces within the material. When a material undergoes shearing stress and corresponding shearing strain, the strain energy density, which is the energy stored per unit volume, is calculated. Within the elastic limit, where the stress is...
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The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...

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Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics
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Published on: January 22, 2020

Quantitative viscoelastic parameters measured by harmonic motion imaging.

Jonathan Vappou1, Caroline Maleke, Elisa E Konofagou

  • 1Biomedical Engineering Department, Columbia University, New York, NY, USA.

Physics in Medicine and Biology
|May 21, 2009
PubMed
Summary
This summary is machine-generated.

This study introduces an ultrasound method to measure tissue elasticity and viscosity. The harmonic motion imaging (HMI) technique accurately estimates viscoelastic properties in phantoms, validated against mechanical testing.

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Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
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Published on: May 10, 2022

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Acoustics

Background:

  • Quantifying soft tissue mechanical properties is crucial for medical diagnostics.
  • Existing elasticity imaging methods face challenges in accurately assessing viscoelasticity.
  • Ultrasound-based techniques offer non-invasive potential for tissue characterization.

Purpose of the Study:

  • To develop and validate an ultrasound-based method for quantitative estimation of viscoelastic properties in soft tissues.
  • To utilize amplitude-modulated harmonic motion imaging (HMI) for measuring shear storage (G') and shear loss modulus (G'').
  • To compare HMI measurements with established mechanical testing methods.

Main Methods:

  • Employing focused ultrasound to generate oscillating acoustic radiation force within a medium.
  • Measuring resulting displacements using an imaging transducer to capture shear wave propagation.
  • Implementing a two-step approach analyzing shear wave properties and stress-strain phase shifts to determine G' and G''.

Main Results:

  • Excellent agreement between input and measured G' and G'' values in numerical phantoms.
  • Good agreement (14% error) for shear storage modulus (G') in gel phantoms compared to rheometry at 10 Hz.
  • Poorer agreement for shear loss modulus (G'') in gel phantoms (55% error), attributed to low G'' values.

Conclusions:

  • The proposed HMI method provides a model-independent, quantitative ultrasound-based approach for elasticity imaging.
  • The technique shows promise for estimating tissue viscoelastic properties, with validation against mechanical testing.
  • Further refinement may be needed to enhance sensitivity for low viscosity tissues.