Multiple pilomatrixoma in Turner syndrome
Alan R Bengtzen1, Hans E Grossniklaus, C Robert Bernardino
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ophthalmic Plastic and Reconstructive Surgery
|May 21, 2009
Summary
Multiple pilomatrixoma, typically rare, appeared in a patient with Turner syndrome. This case highlights the importance of considering Turner syndrome in individuals with numerous pilomatrixoma lesions.
Area of Science:
- Dermatology
- Genetics
- Pediatrics
Background:
- Pilomatrixoma is a common, benign skin tumor originating from the hair follicle matrix.
- It typically presents as a solitary lesion with a low rate of recurrence.
Observation:
- A case study involving a 13-year-old female patient with Turner syndrome.
- The patient presented with ten distinct facial pilomatrixoma lesions over a seven-year period.
- Histopathological examination confirmed all lesions as pilomatrixoma.
Findings:
- The occurrence of multiple pilomatrixoma in this patient is highly unusual.
- The association suggests a potential link between multiple pilomatrixoma and Turner syndrome.
Implications:
- The presence of multiple pilomatrixoma should prompt consideration for underlying genetic conditions like Turner syndrome.
- This finding may aid in earlier diagnosis and management of Turner syndrome in pediatric patients.
- Further research is warranted to explore the genetic and molecular mechanisms connecting pilomatrixoma and Turner syndrome.
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