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Related Experiment Video

Updated: Jun 23, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Abnormal cytogenetics in orbital lipoma.

Lorraine Y Ong¹, Bruce Mercer, Lynda J Campbell

¹Orbital Plastic and Lacrimal Clinic, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. lorraine.ong@gmail.com

Ophthalmic Plastic and Reconstructive Surgery

|May 21, 2009

Summary

Orbital lipomas are rare tumors. Cytogenetic analysis of orbital lipoma revealed chromosome 12 abnormalities, aiding in distinguishing these tumors from normal orbital fat.

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Last Updated: Jun 23, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Area of Science:

Ophthalmology
Oncology
Genetics

Background:

Orbital lipomas are rare benign tumors originating from adipose tissue within the eye socket.
Diagnosis can be challenging due to their rarity and potential for mimicking other orbital masses.

Observation:

A case of orbital lipoma in a 56-year-old male patient is presented.
The patient underwent successful surgical excision of the orbital lipoma.

Findings:

Cytogenetic analysis of the excised orbital lipoma revealed abnormalities of chromosome 12.
These chromosomal abnormalities are consistent with those found in lipomas in other body locations.

Implications:

Cytogenetic analysis can be a valuable tool for differentiating orbital lipomas from normal orbital fat.
This finding may improve diagnostic accuracy and guide treatment strategies for orbital lipomatous lesions.