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Updated: Jun 23, 2026

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
Published on: May 6, 2014
[Ozone therapy for protracted pneumonias]
Abstract:
After 3 weeks or more of treatment, 36 patients who were found to have X-ray signs of pneumonia (pulmonary infiltrative changes, fever, productive cough, weakness) were randomized into two matched groups (a study group and a control one). 77.7 and 55% of control and study group patients changed and continued antibacterial therapy. The study group patients were additionally given intravenous infusions of 400 ml of ozonized sodium chloride solution (pO3) containing 1.6 microg/ml of O3 twice weakly for 21 days. Blood ozonization considerably accelerated the resolution time of X-ray infiltrative changes so that they were undetectable in all study group patients by week 4 while they were only in 61.1% of the control groups. Blood ozonization used in combination with antibiotics permitted caused a sputum negative reaction against Chlamydia and Mycoplasma 2-3 weeks earlier. Infusions of pO3 just after the first ozonization made it possible to eliminate a clinical sign of chronic infection, such as weakness, to accelerate productive cough relief on day 10, and to reduce the number of fever patients. Ozone therapy for protracted pneumonias substantially enhances the efficiency of antibiotic treatment.
Insights
Ozone therapy, combined with antibiotics, significantly speeds up pneumonia recovery. This treatment accelerated the resolution of lung infiltrates and improved patient symptoms, enhancing overall treatment effectiveness.
Area of Science:
- Medical Science
- Pulmonology
- Ozone Therapy
Background:
- Protracted pneumonia presents challenges in treatment, often requiring prolonged antibiotic courses.
- Identifying effective adjunctive therapies to expedite recovery is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of ozone therapy as an adjunct to antibiotic treatment for protracted pneumonia.
- To assess the impact of ozonized sodium chloride solution on radiographic and clinical recovery.
Main Methods:
- 36 patients with X-ray confirmed pneumonia were randomized into a study group (antibiotics + ozonized solution) and a control group (antibiotics only).
- The study group received intravenous infusions of ozonized sodium chloride solution (pO3) twice weekly for 21 days.
- Treatment outcomes were assessed based on radiographic resolution of infiltrates, sputum negativity, and clinical symptoms like fever, cough, and weakness.
Main Results:
- Blood ozonization significantly accelerated the resolution of X-ray infiltrative changes, with all study patients showing undetectable changes by week 4 compared to 61.1% in the control group.
- The study group achieved sputum negativity for Chlamydia and Mycoplasma 2-3 weeks earlier than the control group.
- Ozone therapy led to earlier relief of productive cough (day 10), reduced fever, and elimination of weakness.
Conclusions:
- Ozone therapy, when used adjunctively with antibiotics, substantially enhances the efficiency of treatment for protracted pneumonias.
- Intravenous ozonized sodium chloride solution is a promising adjunctive therapy for improving recovery time and clinical outcomes in pneumonia patients.
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