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Updated: Jun 23, 2026
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Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
Published on: May 19, 2018
Necrotizing lymphadenitis of the neck
S D Micozkadioglu1, A N Erkan, N E Kocer
1Department of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey. denizmicozkadioglu@yahoo.com
B-ENT
|May 22, 2009
Summary
Histiocytic necrotizing lymphadenitis is a rare, benign neck condition causing swollen lymph nodes and fever. This self-limiting disease
Area of Science:
- Pathology
- Oncology
Background:
- Cervical lymphadenopathy is a common clinical finding with diverse etiologies.
- Histiocytic necrotizing lymphadenitis (HNL) is an uncommon, benign condition presenting as neck swelling.
Observation:
- A 25-year-old female presented with a three-month history of neck swelling and fever.
- Physical examination revealed a painless swelling in the posterior cervical region.
Findings:
- Histopathological examination of an excisional lymph node biopsy confirmed HNL.
- Microscopic findings included necrotizing granulomas with prominent histiocytic infiltration.
Implications:
- This case highlights the importance of considering HNL in the differential diagnosis of cervical lymphadenopathy.
- Early diagnosis and recognition of this self-limiting condition can prevent unnecessary invasive investigations.
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