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Updated: Jun 23, 2026

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits
Published on: August 20, 2014
Routine patch testing with the preservative system Kathon CG
A C Groot1, D P Bruynzeel, J G Schroeff
1Departments of Dermatology, Carolus & Willem-Alexander Hospital, PO Box 90152, 5200 MD 's-Hertogenbosch, Amsterdam.
Abstract:
Synopsis Of 1620 patients routinely patch tested with Kathon CG 100 p.p.m. aqua for suspected allergic contact dermatitis, 81 (5.0%) had a positive reaction. Sixty-two reactions (3.8%) were relevant for the dermatitis for which the patient consulted the dermatologist. Most patients were females who presented with dermatitis of the hands and/or face. Forty-six per cent of the patients had become sensitized by using cosmetic products on healthy skin. The other 54% had pre-existing dermatitis, especially atopic dermatitis and irritant dermatitis. Most reactions were caused by moisturizing creams.
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