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Updated: Jun 23, 2026

Isolation and Culture of Primary Endothelial Cells from Canine Arteries and Veins
Published on: November 18, 2016
Secondary tumoural valvulopathy in a dog
Csaba Jakab1, Attila Marcell Szász, Janina Kulka
1Department of Pathology and Forensic Veterinary Medicine, Faculty of Veterinary Medicine, Szent István University, István u. 2, H-1078 Budapest, Hungary. Jakab.Csaba@aotk.szie.hu
Abstract:
This short report describes a case of tricuspid valvular metastasis of canine disseminated histiocytic sarcoma in a 9-year-old female Rottweiler. Immunohistochemically the malignant neoplastic cells gave a strong reaction for vimentin and lysozyme, and showed negativity for serotonin, CD3, CD79a and cytokeratin. The intratumoural microvessels were detected by immunohistochemistry using CD31 and claudin-5. This appears to be the first report of a valvular metastasis of canine malignant histiocytosis.
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