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Updated: Jun 23, 2026
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Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
Published on: February 23, 2017
Surface modification of PDMS by gradient-induced migration of embedded Pluronic
1Microsystem Technology, Department of Engineering Science, Uppsala University, Box 534, The Angstrom Laboratory, 751 21, Uppsala, Sweden. Zhigang.Wu@angstrom.uu.se
Lab on a Chip
|May 22, 2009
Abstract:
We present a simple, flexible, and environmentally friendly approach to modify the PDMS surface by gradient-induced migration of embedded amphiphilic copolymer Pluronic F127 and the hydrophobic interaction between the migrated embedded Pluronic and substrate molecules near the surface. The modified surface is hydrophilic and reduces the nonspecific adsorption of protein significantly.
