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Value of fine-needle aspiration biopsy of salivary gland lesions
Rikke Kølby Christensen1, Kristine Bjørndal, Christian Godballe
1Department of Pathology, Odense University Hospital, Odense, Denmark.
Background:
The aim of this study was to assess the utility of fine-needle aspiration biopsy (FNAB) in the diagnosis and treatment planning of the lesions of the salivary gland.
Methods:
Eight hundred seventy-nine aspiration biopsies of the lesion of the salivary gland over a 10-year period, from 1997 to 2006, were reviewed with special reference to its value in the clinical treatment of patients.
Results:
Cytologic as well as histologic diagnoses of 382 patients were available. In these diagnoses, the sensitivity of malignancy was 83% and specificity was 99%. The positive predictive value was 98%, and the negative predictive value was 97%. The overall accuracy was 93%. The correct subtyping of the benign lesions was 97%, and the exact type-specific concordance of the malignant lesions was 71%.
Conclusion:
Considerable benefit to the patient may result from the cautious use of FNAB of lesions of the salivary gland. The close co-operation between pathologist and surgeon can improve individual treatment.
