Related Experiment Video
Updated: Jun 23, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
[A review of drive system for pulsatile blood pump]
1Department of instrumentation, Shanghai Jiaotong University, Shanghai, 200240.
Abstract:
Many varieties of pulsatile blood pumps exist in the fields of artificial hearts and ventricular assist devices. Effective sorts can be achieved with the differences in power source and transmission mechanism. Horizontal comparison across different pulsatile blood pumps, together with evolution of similar species is studied to find the commonness and evolution laws for pulsatile blood pumps. After a review of typical pulsatile blood pumps from the angle of power source and transmission mechanism, much analysis is focus on a pulsatile drive structure with flexible electro-hydraulic transmission, and importance of hydraulic transmission to improve the implantation property of pulsatile blood pumps is discussed. Finally new application of electro-hydraulic pulsatile blood pumps in the future, such as the application in Direct Mechanical Ventricular Assistant Device (DMVAD) is given.
Related Concept Videos
Blood Flow
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
ATP Driven Pumps II: P-type Pumps
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
ATP Driven Pumps III: V-type Pumps
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
Overview of Systemic and Pulmonary Circulation
The oxygenated blood is sent...

