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A Seamless Cloning Approach for Porcine Reproductive and Respiratory Syndrome Virus Expression Vector Construction
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[Porcine epidemic diarrhea].

O V Sergeev

    Voprosy Virusologii
    |May 23, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Porcine epidemic diarrhea (PED) causes severe economic losses in swine. This overview examines the use of Vero cell-propagated PED virus strains as potential live vaccines.

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    Area of Science:

    • Veterinary Virology
    • Swine Disease Research

    Background:

    • Porcine epidemic diarrhea (PED) is a significant swine disease.
    • The causative agent is a swine coronavirus.
    • PED results in substantial economic losses for the pork industry.

    Purpose of the Study:

    • To review current data on porcine epidemic diarrhea (PED).
    • To assess the potential of cell-propagated PED virus strains as live vaccines.

    Main Methods:

    • Literature review of available data on PED.
    • Analysis of PED virus propagation in Vero cell cultures.
    • Evaluation of PED virus strains for vaccine potential.

    Main Results:

    • The overview compiles existing information on PED and its viral agent.
    • Discussion includes the economic impact of the disease.
    • The feasibility of using serially Vero cell propagated PED virus strains as live vaccines is explored.

    Conclusions:

    • Further research is needed to confirm the efficacy and safety of Vero cell-propagated PED virus strains as live vaccines.
    • Cell-propagated PED virus strains show promise for vaccine development.
    • Addressing economic losses from PED is a priority in swine health management.