Related Experiment Video
Updated: Jun 23, 2026

11:02
Presynaptically Silent Synapses Studied with Light Microscopy
Published on: January 4, 2010
Spreading the silence
1Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. janet.partridge@stjude.org
Developmental Cell
|May 23, 2009
Abstract:
RITS (RNA-induced initiation of transcriptional gene silencing complex) plays diverse roles in heterochromatin regulation: silencing transcription by recruitment of chromatin modifiers and destroying transcripts by RNAi. In a recent issue of Molecular Cell, Li et al. now show that the polymerization of Tas3, a component of RITS, contributes to the spreading of silencing mediated by RITS.
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