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Margin of Error01:27

Margin of Error

The margin of error is also called the maximum error of an estimate. The margin of error is the maximum possible or expected difference between the observed sample parameter value and the actual population parameter value. For proportion, it is the maximum difference between the value of sample proportion obtained from the data and the true value of population proportion. As the true value of the population parameter is not known, the margin of error is calculated using the sample statistic.
Gap Junctions01:37

Gap Junctions

Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
Gap Junctions01:27

Gap Junctions

The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
Hindsight Biases01:12

Hindsight Biases

Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now?
Common Leveling Mistakes and Errors01:17

Common Leveling Mistakes and Errors

A survey team is tasked with determining the elevation difference between points Point A and Point B, separated by uneven terrain. They use a leveling instrument and a leveling rod.Common MistakesMisreading the Rod: During a backsight reading at Point A, the instrumentman observes the rod partially obscured by tall grass. Instead of reading 1.135 m, they mistakenly record 1.735 m due to the misalignment of the crosshair with the wrong graduation. This error adds 0.600 m to all subsequent...
Self-Discrepancy Theory02:45

Self-Discrepancy Theory

One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.

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Related Experiment Video

Updated: Jun 23, 2026

Using a Virtual Reality Walking Simulator to Investigate Pedestrian Behavior
06:38

Using a Virtual Reality Walking Simulator to Investigate Pedestrian Behavior

Published on: June 9, 2020

Mind the gaps.

C A Rees1

  • 1Tyndalls Park Children's Centre, Bristol, UK. drcarees@doctors.org.uk

Archives of Disease in Childhood
|May 23, 2009
PubMed
Summary
This summary is machine-generated.

Managing the unknown is crucial for future healthcare. Recognizing and addressing knowledge gaps in specialized medical practice is essential for patient safety and scientific advancement.

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Area of Science:

  • Medical Practice and Healthcare Systems
  • Knowledge Management in Medicine

Background:

  • Increasing specialization and reliance on clinical investigations risk overlooking critical knowledge and service gaps.
  • Devaluation of fundamental clinical skills like history taking and examination exacerbates these blind spots.

Purpose of the Study:

  • To highlight the risks associated with unrecognised gaps in medical knowledge and services.
  • To advocate for professional structures that minimize blind spots in healthcare.
  • To emphasize the importance of managing the unknown for patient safety and progress.

Main Methods:

  • Conceptual analysis of current trends in medical practice.
  • Discussion of the implications of specialization and regulation on knowledge management.
  • Evaluation of professional structures for their effectiveness in identifying and addressing knowledge gaps.

Main Results:

  • Unrecognised gaps in medical knowledge and services pose significant hazards to patient safety.
  • Current trends may inadvertently widen these gaps, hindering progress.
  • Proactive management of the unknown is as vital as prudent application of existing knowledge.

Conclusions:

  • Professional practice must evolve to actively identify and manage knowledge deficits.
  • Robust systems are needed to evaluate both practice and the structures that support it.
  • Addressing the implications of what is not known is fundamental to safe and progressive healthcare.