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Discovering misattributed paternity in living kidney donation: prevalence, preference, and practice
Ann Young1, Sang Joseph Kim, Eric M Gibney
1Division of Nephrology, University of Western Ontario, London, ON, Canada.
Transplantation
|May 23, 2009
Summary
Discovering misattributed paternity in living kidney donation is uncommon, affecting 1-3% of father-child pairs. Opinions on disclosing this sensitive information to donors and recipients vary significantly among professionals.
Area of Science:
- Transplant Surgery
- Genetics
- Medical Ethics
Background:
- Living kidney donation evaluations occasionally reveal a lack of biological relationship between father-child pairs.
- Misattributed paternity can impact donor-recipient compatibility and has ethical implications.
Purpose of the Study:
- To determine the frequency of misattributed paternity in father-child living kidney donor-recipient pairs.
- To explore transplant professionals' opinions on disclosing this information.
- To understand current practices for handling such discoveries in Canada.
Main Methods:
- Analysis of data from the United Network for Organ Sharing and Canadian Organ Replacement Registry.
- Survey of 102 potential donors, recipients, and transplant professionals regarding disclosure.
- Interviews with transplant professionals from 13 Canadian centers on handling practices.
Main Results:
- Misattributed paternity occurs in 1-3% of father-child living kidney donor-recipient pairs (0.25-0.5% of all living kidney donations).
- Opinions on disclosure are divided: 23% strongly favor, 24% strongly oppose.
- Current practices for disclosure vary across transplant centers.
Conclusions:
- Discovering misattributed paternity in living kidney donation, while uncommon, does occur.
- There is significant variability in professional opinions and practices regarding disclosure.
- Further discussion among transplant professionals is needed to establish best practices and policies.
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