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Published on: August 19, 2012
Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation
Hailong Zhang1, Yong Ma, Xue-Long Sun
1Department of Chemistry, Cleveland State University, Cleveland, OH 44115, USA.
Abstract:
An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBS buffer (pH 7.4) at room temperature.

