Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Cellular Adaptation IV: Dysplasia and Metaplasia01:24

Cellular Adaptation IV: Dysplasia and Metaplasia

DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of Alzheimer's Disease subjects with expanded non-genetically modified autologous natural killer cells (SNK01): a phase I study.

Alzheimer's research & therapy·2025
Same author

Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females.

Genetics·2024
Same author

Premeiotic pairing of homologous chromosomes during <i>Drosophila</i> male meiosis.

Proceedings of the National Academy of Sciences of the United States of America·2022
Same author

Isolation of stage-specific germ cells using FACS in Drosophila germarium.

Methods in cell biology·2020
Same author

A Genome-Wide Screen for Dendritically Localized RNAs Identifies Genes Required for Dendrite Morphogenesis.

G3 (Bethesda, Md.)·2016
Same author

tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription.

The EMBO journal·2015

Related Experiment Video

Updated: Jun 23, 2026

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia
08:40

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Published on: April 19, 2024

[Development hip dysplasia. Knowledge in pediatricians].

Luis E Montes1, Rufino Menchaca, Ana María Valles

  • 1Hospital Infantil de las Californias. montesmd@hotmail.com

Acta Ortopedica Mexicana
|May 26, 2009
PubMed
Summary
This summary is machine-generated.

Paediatricians in Tijuana recognize the importance of early diagnosis for developmental hip dysplasia (DHD) in newborns, but a knowledge gap exists. Further training is needed to improve recognition and management of DHD.

More Related Videos

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

Related Experiment Videos

Last Updated: Jun 23, 2026

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia
08:40

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Published on: April 19, 2024

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
07:43

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy

Published on: July 2, 2021

Area of Science:

  • Paediatrics
  • Orthopaedics
  • Medical Education

Context:

  • Developmental hip dysplasia (DHD) diagnosis relies on newborn clinical evaluation.
  • Early intervention is crucial for favorable outcomes; delayed diagnosis leads to severe consequences.
  • Assessing paediatrician knowledge is vital for effective DHD management.

Purpose:

  • To evaluate the theoretical knowledge of paediatricians in Tijuana, Mexico, regarding DHD.
  • To identify gaps in understanding epidemiology, risk factors, diagnosis, and early management of DHD.

Summary:

  • A 13-item questionnaire assessed DHD knowledge in 77 Tijuana paediatricians.
  • While 100% agreed on the importance of early diagnosis, only 22% achieved a satisfactory score (mean 6/12 correct answers).
  • A significant deficit in theoretical knowledge regarding DHD was observed.

Impact:

  • Highlights a critical need for enhanced paediatrician training in DHD recognition and management.
  • Underscores the importance of college boards assessing and reinforcing essential DHD knowledge.
  • Aims to improve early detection and treatment of DHD, leading to better patient prognoses.