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Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes
12:47

Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes

Published on: May 14, 2012

[Totipotency of the peripheral lymphocyte and its application]

Hiroshi Wakao1

  • 1Environmental Biology, Graduate School of Medicine Hokkaido University, W7N15 Kita-ku, Sapporo 060-8638, Japan.

Seikagaku. the Journal of Japanese Biochemical Society
|May 26, 2009
PubMed
Abstract

No abstract available in PubMed .

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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