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Updated: Jun 22, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
[Epidemiology of invasive candidiasis in pediatric and adult populations]
Amalia Del Palacio1, Julia Villar, Almudena Alhambra
1Servicio de Microbiología, Unidad de Micología, Hospital Universitario 12 de Octubre, Madrid, España. apalacioh.hdoc@salud.madrid.org
Background:
Invasive candidiasis (IC) is the most frequent fungal disease in children and adults.
Aims:
To critically review and update the current epidemiology of Candida spp. disease in neonates, children and adults (critically ill patients and in oncohematologic patients and in solid organ transplant recipients).
Methods:
We searched the PubMed/Medline, discussing the current data.
Results And Conclusions:
IC is associated with high attributable morbimortality and increased healthcare costs. In the last decades the incidence of invasive Candida spp. disease has increased in critically ill patients, has decreased in oncohematologic patients, although currently the involvement of non-albicans Candida species in the etiology of this disease is increasing steadily.
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