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Related Experiment Videos

WOBB.C: a portable software package for defining and searching ambiguous sequence patterns.

J M Claverie1, I Sauvaget

  • 1Biocomputing Unit, Institut Pasteur, Paris, France.

Protein Sequences & Data Analysis
|August 1, 1991
PubMed
Summary

WOBB.C is a C-written program for building and finding ambiguous sequence patterns in protein and nucleotide data. Its flexible interface and portability enhance biosequence analysis through multiple pattern definition methods.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Sequence Analysis

Background:

  • Accurate identification of sequence patterns is crucial for understanding biological functions.
  • Existing tools may lack flexibility or portability in defining and searching sequence patterns.

Purpose of the Study:

  • To introduce WOBB.C, a novel software package for constructing and locating ambiguous sequence patterns.
  • To provide a portable and flexible tool for biosequence analysis.

Main Methods:

  • Utilizes the perceptron algorithm for sequence searching, as described by Stormo et al. (1982).
  • Offers three distinct methods for pattern definition: automatic from multi-alignment, interactive from a string, and script-based from a text file.

Main Results:

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  • WOBB.C facilitates the manipulation and location of ambiguous sequence patterns within large datasets.
  • The software's design emphasizes portability and a user-friendly, adaptable interface.

Conclusions:

  • WOBB.C offers an effective and versatile solution for ambiguous sequence pattern analysis in bioinformatics.
  • The program's flexible pattern definition and search capabilities support diverse research needs in sequence analysis.