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The Toronto Root bioprosthesis: midterm results in 186 patients
Sven Lehmann1, Thomas Walther, Sergey Leontyev
1Department of Cardiac Surgery, University of Leipzig, Heartcenter, Leipzig, Germany. sven.lehmann@med.uni-leipzig.de
The Annals of Thoracic Surgery
|May 26, 2009
Summary
The Toronto Root bioprosthesis demonstrated safety and effectiveness in full aortic root replacement, showing improved patient outcomes and promising long-term durability due to its anticalcification treatment.
Area of Science:
- Cardiovascular Surgery
- Bioprosthetic Valves
- Aortic Valve Disease
Background:
- The Toronto Root bioprosthesis with BiLinx anticalcification treatment was introduced in 2001 for aortic valve disease and aortic pathology.
- This study reviews patients who underwent full root replacement using this device.
Purpose of the Study:
- To evaluate the safety and clinical outcomes of the Toronto Root bioprosthesis in full root replacement procedures.
- To assess the hemodynamic function and survival rates in patients receiving this bioprosthesis.
Main Methods:
- A retrospective review of 186 patients who received the Toronto Root bioprosthesis between June 2001 and November 2007.
- Patients underwent full root replacement, often with additional aortic or cardiac procedures.
- Mean follow-up was 50 months, with clinical and echocardiographic data evaluated.
Main Results:
- All patients experienced clinical improvement (at least one NYHA class).
- Mean transvalvular velocity was 2.1 m/s with a mean gradient of 9.6 mm Hg.
- Five-year survival was 83.3%, with isolated aortic root surgery patients showing 90.3% survival.
Conclusions:
- The Toronto Root bioprosthesis is safe and offers good clinical and hemodynamic function for full aortic root replacement.
- The BiLinx anticalcification treatment suggests potential for favorable long-term durability.