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Published on: April 28, 2016
Ghrelin and its biological effects on pigs
Xiao-Ying Dong1, Jian Xu, Sheng-Qiu Tang
1College of Yingdong Bioengineering, Shaoguan University, Zhenjiang District, Shaoguan, Guangdong, China.
Peptides
|May 26, 2009
Summary
Ghrelin, a peptide hormone, regulates crucial functions in pigs, including appetite and growth. This review details ghrelin
Area of Science:
- Endocrinology and Animal Physiology
Background:
- Ghrelin is a 28-amino acid peptide hormone.
- It exerts effects by binding to the growth hormone secretagogue receptor (GHS-R).
Purpose of the Study:
- To present recent research on ghrelin in pigs.
- To cover ghrelin structure, distribution, GHS-R, biological functions, and regulatory mechanisms.
Main Methods:
- Literature review of contemporary research on ghrelin in pigs.
Main Results:
- Ghrelin regulates food intake, body weight, GI motility, hormone secretion, glucose release, cardiovascular functions, enzyme release, cell proliferation, and reproduction in pigs.
- Ghrelin induces adipocyte and hepatocyte proliferation in primary cultured piglets.
Conclusions:
- Ghrelin plays a significant role in various physiological processes in pigs.
- Further research into ghrelin's structure, distribution, receptor interactions, and regulatory mechanisms is warranted.
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