Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary and motile cilia in the efferent ductules: a role for IFT88 in maintaining male fertility.

Cellular and molecular life sciences : CMLS·2026
Same author

Towards cervical AI of sheep with stored semen: latest insights and future developments.

The Journal of reproduction and development·2026
Same author

Proteomic datasets of three <i>Hermetia illucens</i> Larvae Forms (Fresh, Dried, and Protein concentrate).

Data in brief·2026
Same author

The P2X4 purinergic receptor controls the autophagy-related release of small extracellular vesicles from mammary cancer cells under hypoxia.

Cell communication and signaling : CCS·2026
Same author

Weakening of hen egg vitelline membrane during egg storage at room temperature is associated with modifications of its mass, thickness and proteomic profile.

Food research international (Ottawa, Ont.)·2026
Same author

Immunohistochemical Evidence of Telocytic Stroma Associated with Tumor Grade and Acinar Heterogeneity in Prostate Cancer.

International journal of molecular sciences·2026

Related Experiment Video

Updated: Jun 22, 2026

Analysis of Epididymal Protein Synthesis and Secretion
10:23

Analysis of Epididymal Protein Synthesis and Secretion

Published on: August 25, 2018

Mammalian epididymal proteome.

Jean-Louis Dacheux1, Clémence Belleannée, Russell Jones

  • 1INRA-CNRS 6175, Nouzilly, France. jdacheux@tours.inra.fr

Molecular and Cellular Endocrinology
|May 26, 2009
PubMed
Summary

Spermatozoa gain motility and fertilization abilities in the epididymal duct, a crucial process for male fertility. Comparative proteomic studies across mammals reveal conserved sperm modifications.

More Related Videos

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
09:30

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa

Published on: December 30, 2014

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
08:30

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns

Published on: December 12, 2025

Related Experiment Videos

Last Updated: Jun 22, 2026

Analysis of Epididymal Protein Synthesis and Secretion
10:23

Analysis of Epididymal Protein Synthesis and Secretion

Published on: August 25, 2018

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa
09:30

Phosphopeptide Analysis of Rodent Epididymal Spermatozoa

Published on: December 30, 2014

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
08:30

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns

Published on: December 12, 2025

Area of Science:

  • Reproductive Biology
  • Mammalian Physiology
  • Proteomics

Background:

  • Spermatozoa undergo final differentiation in the epididymal duct, acquiring motility and fertilizing capacity.
  • Understanding male germ cell maturation is essential for controlling male fertility.
  • Comparative analyses across species can identify conserved, non-species-specific sperm modifications.

Purpose of the Study:

  • To conduct comparative proteomic studies of the epididymis in several mammalian species.
  • To identify common sperm modifications occurring during epididymal transit.
  • To leverage global biological approaches like transcriptomics and proteomics for insights into male fertility.

Main Methods:

  • Proteomic analysis of epididymal tissues from multiple mammalian species, including humans.
  • Comparative analysis of proteomic data to identify conserved protein expression patterns.
  • Utilizing global biological approaches to study sperm modifications.

Main Results:

  • Proteomic profiling revealed conserved molecular changes in spermatozoa during epididymal transit across different mammalian species.
  • Identification of specific proteins and pathways involved in sperm maturation.
  • Data provides a foundation for understanding species-conserved mechanisms of male fertility.

Conclusions:

  • Comparative proteomic studies of the epididymis are valuable for understanding conserved aspects of male fertility.
  • The epididymis plays a critical role in sperm functional maturation through conserved biological processes.
  • These findings contribute to a deeper understanding of male reproductive biology and potential fertility interventions.