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Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

Testosterone therapy in men.

Aikaterini Theodoraki¹, Pierre-Marc Bouloux

¹Centre for Neuroendocrinology, Royal Free Campus, University College Medical School, Rowland Hill Street, London NW3 2PF, UK. k_theodoraki@yahoo.gr

Menopause International

|May 26, 2009

Summary

This summary is machine-generated.

Testosterone deficiency (hypogonadism) causes various symptoms corrected by replacement therapy. Further research is needed on testosterone replacement

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Area of Science:

Endocrinology and Men's Health
Molecular Biology

Background:

Androgens, like testosterone, are crucial for numerous physiological functions.
Testosterone deficiency (hypogonadism) in men leads to diverse symptoms and signs.
The impact of hypogonadism varies with age at onset.

Purpose of the Study:

To review the physiological roles of androgens and testosterone.
To discuss the clinical implications of hypogonadism and its management.
To explore emerging therapeutic strategies targeting the androgen receptor.

Main Methods:

Review of recent studies on testosterone's relation to aging, metabolic syndrome, type 2 diabetes, obesity, and survival.
Examination of molecular targets of testosterone.
Analysis of ongoing clinical trials for selective androgen receptor modulators (SARMs).

Main Results:

Testosterone replacement therapy corrects hypogonadism symptoms.
Further large-scale, long-term studies are required to clarify testosterone replacement therapy's effects on aging and metabolic conditions.
Selective androgen receptor modulators (SARMs) are under clinical investigation as potential therapeutics.

Conclusions:

Testosterone plays a vital role in male physiology and health.
Close monitoring is advised during testosterone replacement therapy.
Targeting the androgen receptor with agents like SARMs represents a promising area for future therapeutic development.