Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Scattering by nanoplasmonic mesoscale assemblies.

Journal of the Optical Society of America. A, Optics, image science, and vision·2025
Same author

Asymptotic behavior of the reflectance of a narrow beam by a plane-parallel slab.

Journal of the Optical Society of America. A, Optics, image science, and vision·2025
Same author

Mouse tracking performance: A new approach to analyzing continuous mouse tracking data.

Behavior research methods·2023
Same author

Hashtags as signals of political identity: #BlackLivesMatter and #AllLivesMatter.

PloS one·2023
Same author

Radiance backscattered by a strongly scattering medium in the high spatial frequency limit.

Journal of the Optical Society of America. A, Optics, image science, and vision·2022
Same author

Modeling broadband cloaking using 3D nano-assembled plasmonic meta-structures.

Optics express·2020

Related Experiment Video

Updated: Jun 22, 2026

Scattering And Absorption of Light in Planetary Regoliths
11:34

Scattering And Absorption of Light in Planetary Regoliths

Published on: July 1, 2019

Comparison of light scattering models for diffuse optical tomography.

Pedro González-Rodríguez1, Arnold D Kim

  • 1Universidad Carlos III de Madrid, Escuela Politécnica Superior, Grupo de Modelización y Simulación Numérica, Avenida de Universidad 30, 28911 Leganés, Spain.

Optics Express
|May 26, 2009
PubMed
Summary
This summary is machine-generated.

We compared five light propagation models for diffuse optical tomography imaging. Approximations like the generalized Fokker-Planck-Eddington equation offer computational savings and good image reconstruction, despite some cross-talk.

More Related Videos

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

Related Experiment Videos

Last Updated: Jun 22, 2026

Scattering And Absorption of Light in Planetary Regoliths
11:34

Scattering And Absorption of Light in Planetary Regoliths

Published on: July 1, 2019

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
12:24

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Published on: July 17, 2012

Area of Science:

  • Biomedical Optics
  • Medical Imaging
  • Computational Science

Background:

  • Diffuse optical tomography (DOT) is a non-invasive imaging technique.
  • Accurate modeling of light propagation in tissues is crucial for DOT.
  • The radiative transport equation (RTE) is a highly accurate but computationally intensive model.

Purpose of the Study:

  • To evaluate the performance of different light propagation models in DOT.
  • To compare approximate models against the RTE for image reconstruction.
  • To assess computational efficiency and image quality.

Main Methods:

  • Image reconstruction using the transport-backtransport method.
  • Simulated DOT data based on the RTE.
  • Comparison of five light propagation models: RTE, delta-Eddington, Fokker-Planck, Fokker-Planck-Eddington, and generalized Fokker-Planck-Eddington.

Main Results:

  • All tested models produced good image reconstructions for absorption and scattering coefficients.
  • Approximate models provided significant computational savings compared to the RTE.
  • All models exhibited cross-talk between absorption and scattering coefficient images.

Conclusions:

  • Approximate models are viable alternatives to the RTE for DOT, offering computational benefits.
  • The generalized Fokker-Planck-Eddington approximation yielded the best image reconstruction quality among the approximations tested.
  • Further research into mitigating cross-talk in DOT imaging is warranted.