Related Experiment Video
Updated: Jun 22, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Nail dystrophy and bony involvement in chronic sarcoidosis
Frank Santoro1, Steven Brett Sloan
1University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Abstract:
A patient with a chronic course of sarcoidosis with pulmonary and cutaneous involvement presented with dystrophy involving 20 nails. Histologic analysis revealed noncaseating granulomas consistent with nail sarcoidosis, and radiologic evaluation revealed bony cysts typical of sarcoidosis. Nail dystrophy in sarcoidosis is rare; however, when present, it signifies a chronic course of disease. We review the incidence, histopathologic correlation to clinical symptoms, radiologic findings, differential diagnosis, and treatment of nail dystrophy in sarcoidosis.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Accessory Structures of the Skin: Nails
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
Chronic Kidney Disease II: Clinical Manifestations
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...