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Historical reflections on hypertension.

V Vertes¹, L Tobias, S Galvin

¹Department of Special Programs, Mt. Sinai Medical Center of Cleveland, Ohio.

|September 1, 1991

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Hypertension, a major cardiovascular risk factor affecting 60 million Americans, accelerates atherosclerosis and leads to serious health issues. This article reviews its history, focusing on blood pressure measurement, treatment advancements, and the roles of the kidney and renin-angiotensin-aldosterone system.

Area of Science:

Cardiology
Nephrology
Vascular Biology

Background:

Hypertension is a significant risk factor for cardiovascular disease, impacting 60 million Americans.
It accelerates atherosclerosis, leading to strokes, heart attacks, heart failure, renal failure, and peripheral vascular disease.

Observation:

The first documented blood pressure measurement occurred in 1733.
The article examines historical landmarks in hypertension research.

Findings:

Recent pharmacologic approaches to hypertension treatment are discussed.
The roles of the kidney and the renin-angiotensin-aldosterone system in hypertension are explored.

Implications:

Understanding hypertension's history and pathophysiology is crucial for effective management.

Related Experiment Videos

This review provides insights into current and historical treatment strategies for hypertension.