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Skin-type adnexal tumor with trichoblastic germinative differentiation in the breast: a case report
Ozay Gököz1, Loretta Presenti, Giuseppina Gambacorta
1Department of Pathology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey.
International Journal of Surgical Pathology
|May 27, 2009
Abstract:
Adnexal tumors with follicular differentiation in the breast parenchyma are rarely encountered. The authors present a unique case arising in a 64-year-old woman, in whom they observed composite differentiation toward follicular germinative cells of the hair follicle with focal areas of outer root sheath differentiation and pilar-type keratinization. The histogenesis of this tumor is analyzed in light of the peculiar pathological, immunohistochemical, and molecular genetic findings.