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Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...

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Related Experiment Video

Updated: Jun 22, 2026

Optimizing the Modified No-Scalpel Vasectomy Technique
04:47

Optimizing the Modified No-Scalpel Vasectomy Technique

Published on: October 18, 2024

Update on male contraception.

Rajesh K Naz1, Shon Rowan

  • 1Robert C. Byrd Health Sciences Center North, Room 2084, West Virginia University, School of Medicine, Morgantown, WV 26506-9186, USA. Rnaz@hsc.wvu.edu

Current Opinion in Obstetrics & Gynecology
|May 27, 2009
PubMed
Summary
This summary is machine-generated.

New male contraceptives are emerging, with hormonal and non-hormonal options in development. These advancements aim to provide reversible, effective birth control for men, moving beyond condoms and vasectomy.

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Area of Science:

  • Reproductive Health
  • Contraception Research
  • Men's Health

Background:

  • Current male contraception relies on barrier methods (condoms) and permanent surgical options (vasectomy).
  • Men express a desire for greater involvement in contraception decisions.
  • Existing methods have limitations, including reliability issues and permanence.

Purpose of the Study:

  • To review existing male contraceptive options.
  • To explore recent advancements and future developments in male contraception.

Main Methods:

  • Review of current literature on male contraceptive methods.
  • Analysis of ongoing clinical trials for hormonal and non-hormonal agents.
  • Examination of research into contraceptive vaccines for men.

Main Results:

  • Condoms are coital-dependent and have failure risks; vasectomy is permanent.
  • Hormonal contraceptives (androgen derivatives) are in clinical trials.
  • Non-hormonal methods and vaccines are under investigation in animal models.
  • The ideal male contraceptive is sought: reversible, effective, coital-dependent, and without side effects on libido or androgen levels.

Conclusions:

  • Male hormonal contraception shows promise for future availability.
  • Non-hormonal strategies, including contraceptive vaccines, represent an exciting area of ongoing research.