Related Experiment Video
Updated: Jun 22, 2026

Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle
Published on: November 4, 2011
[Experience in the treatment of iron deficiency anemia with ferro-folgamma]
Abstract:
The efficiency of therapy with the iron-containing preparation Ferro-Folgamma (Vervag Pharma, Germany) was evaluated in 62 men and women aged from 18 to 82 years with iron-deficiency anemia. Criteria for the efficiency were changes in clinical symptoms of anemia, hemoglobin level, erythrocyte and reticulocyte counts, packed cell volume, erythrocyte indices (mean erythrocyte volume, average content and concentration of hemoglobin in erythrocytes), erythropoietin level, and characteristics of iron metabolism (serum iron and ferritin levels, total iron-binding capacity of the serum, coefficient of ferritin saturation with iron), and drug tolerance. It was shown that Ferro-Folgamma is fairly well tolerated by the patients and produces good therapeutic effect when used to treat and prevent iron-deficiency anemia. Also, the study demonstrated that blood erythropoietin level being a sensitive indicator of hypoxia, it may be used as one of the most important criteria for the assessment of treatment efficiency in patients with iron-deficiency anemia.
Related Concept Videos
The Early Endosome: Endocytosis of Transferrin
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
