[Immunotherapy effect in allergic rhinitis]
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Updated: Jun 22, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
Mevludin Mekić1, Ljiljana Smilić
1Klinika za bolesti srca i reumatizam, Klinicki Centar Univerziteta u Sarajevu. mevludinmekic@yahoo.com
Abstract:
Immunotherapy was introduced as a method into the respiratory system allergies therapy as early as 1911 by Freeman and Noon, who applied it with the patients suffering from pollen rhinitis. Immunity effects of the therapy are basically, suppression of the allergen-specific IgE antibodies synthesis, stimulation of allergen-specific IgG antibodies synthesis, as well as suppression of antigen specific T cell response. Objective of the work was to show efficiency of the immunotherapy in allergic rhinitis treatment through leukocyte formula, total amount of IgE and skin allergy tests. Research results show decrease in eosinophile count in the leukocyte formula, decrease of the total amount of IgE, and decrease of papule and erythema in allergy testing. Immunotherapy is of great importance in the allergic rhinitis therapy and it should be applied wisely.
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