Related Experiment Video

Updated: Jun 22, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Cerebral MRI findings in a cohort of ex-preterm and control adolescents

Zoltan Nagy1, Baldvin Jónsson

  • 1Department of Woman and Child Health, Neonatalogy, Karolinska Institute, Stockholm, Sweden. zoltan.nagy@ki.se

Acta Paediatrica (Oslo, Norway : 1992)
|May 28, 2009
PubMed

Insights

Adolescents born preterm had fewer brain abnormalities on MRI than expected, likely due to minimally invasive neonatal care and Swedish social structures. This study tracked preterm infants long-term.

Area of Science:

  • Neuroimaging
  • Pediatric Neurology
  • Developmental Pediatrics

Background:

  • Preterm birth is a significant risk factor for neurodevelopmental challenges.
  • Cerebral magnetic resonance imaging (MRI) is crucial for assessing brain structure in preterm infants.
  • International comparisons of neuroimaging outcomes in preterm populations are essential for understanding variations in care and outcomes.

Purpose of the Study:

  • To compare cerebral magnetic resonance imaging (MRI) findings in adolescents born preterm with international cohort data.
  • To investigate the long-term structural brain outcomes of individuals born preterm.
  • To identify potential factors influencing neuroimaging results in ex-preterm individuals.

Main Methods:

  • Prospective, long-term follow-up study of preterm-born infants.
  • Cerebral MRI examinations (1.5T scanner, T1- and T2-weighted images) performed on ex-preterm and control participants.
  • Independent and consensus review of MRI scans by experienced neuroradiologists.

Main Results:

  • A low overall rate of brain abnormalities (21/143 scans), mostly mild.
  • Ex-preterm adolescents showed mild white matter loss or gliosis, with some having incidental findings.
  • No significant relationship found between the extent/severity of injury and being born small for gestational age.

Conclusions:

  • The rate of structural brain abnormalities in Swedish adolescents born preterm was lower than reported internationally.
  • Minimally invasive neonatal care practices in Sweden may contribute to better neuroimaging outcomes.
  • Distinct social structures in Sweden could also play a role in the observed lower rates of abnormalities.
Abstract

More Related Videos

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...