Influence of homogenization on emulsion stability
H Saunal1, J P Laget, D E Alvarado
1Institut Européen des Sciences Pharmaceutiques Industrielles de Montpellier, 15 avenue Charles Flahaut, 34060 Montpellier-Cédex, France.
International Journal of Cosmetic Science
|May 28, 2009
Summary
Different homogenizers produced more stable emulsions than a propeller mixer, though exceptions occurred. Mechanisms explaining these reversals involve mechanical energy, interfacial film deficiency, or altered emulsifier concentration.
Area of Science:
- Colloid and Surface Science
- Materials Science
- Chemical Engineering
Background:
- Emulsion stability is crucial in various industries.
- Manufacturing methods significantly impact emulsion properties.
- Understanding emulsifier behavior is key to formulation.
Purpose of the Study:
- To compare the efficacy of different homogenization techniques in emulsion preparation.
- To investigate the influence of manufacturing procedures on emulsion stability.
- To elucidate the mechanisms behind observed stability variations.
Main Methods:
- Preparation of emulsions using a propeller mixer, labyrinth homogenizer, and valve homogenizer.
- Utilized three oil phases and fifteen emulsifier pairs across a range of hydrophilic-lipophilic balance (HLB) values.
- Assessed emulsion stability based on manufacturing procedures.
Main Results:
- Labyrinth and valve homogenizers generally yielded more stable emulsions compared to the propeller mixer.
- Reversals in stability were observed, with the propeller mixer sometimes producing more stable emulsions.
- Suggested mechanisms for stability reversals include modifications in oil/emulsifier interactions, interfacial film deficiency, and altered aqueous phase emulsifier concentration.
Conclusions:
- Homogenizer type critically influences emulsion stability.
- Mechanical energy and emulsifier concentration play complex roles in emulsion stabilization.
- Further research into interfacial phenomena is needed to fully understand emulsion behavior.
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