Related Experiment Video
Updated: Jun 22, 2026

06:13
Vertical T-maze Choice Assay for Arthropod Response to Odorants
Published on: February 14, 2013
The evaluation of underarm deodorants
1Beecham Products Research Department, Randalls Road, Leatherhead, Surrey KT22 7RX.
International Journal of Cosmetic Science
|May 28, 2009
Summary
High-concentration ethanol effectively reduces underarm odor for up to 24 hours. Combining ethanol with antimicrobial agents or zinc ricinoleate further enhances deodorant effects, as confirmed by clinical trials.
Area of Science:
- Cosmetic Science
- Microbiology
- Dermatology
Background:
- Axillary malodor is a common concern, often linked to bacterial activity.
- Deodorant efficacy relies on reducing odor-causing bacteria or absorbing odor molecules.
Purpose of the Study:
- To evaluate the efficacy of ethanol and other ingredients in reducing axillary malodor.
- To compare clinical odor assessment with microbiological techniques.
Main Methods:
- Double-blind, cross-over trials with trained assessors evaluating axillary malodor on a 0-10 scale.
- Inclusion of antimicrobial agents (chlorhexidine, Triclosan, aluminium chlorhydrate) and an odor absorber (zinc ricinoleate).
- Correlation analysis between odor scores and axillary bacterial status using the replipad technique.
Main Results:
- Ethanol (60% and 99% w/w) significantly reduced axillary odor for up to 24 hours.
- Antimicrobial agents and zinc ricinoleate enhanced odor reduction.
- A strong correlation was observed between odor scores and bacterial load for biocidal systems.
- Triclosan showed deodorant efficacy despite suboptimal performance in skin flora sampling.
Conclusions:
- Ethanol-based formulations are effective deodorants.
- Clinical odor assessment remains the gold standard for evaluating deodorant efficacy, surpassing predictive microbiological methods.
Related Concept Videos
Assessing Body Temperature - Axilla
Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
Surface Membrane Barriers
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

