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High-resolution J-scaling nuclear magnetic resonance spectra in inhomogeneous fields via intermolecular
Yanqin Lin1, Zhong Chen, Shuhui Cai
1Department of Physics, State Key Laboratory of Physical Chemistry of Solid Surface, and Fujian Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, PR China.
Abstract:
High-resolution nuclear magnetic resonance (NMR) spectroscopy with information on chemical shifts and J-coupling constants is a sensitive tool for studying physical, chemical, and biological properties of materials at the molecular level. In this paper, a pulse sequence is developed for acquiring high-resolution NMR spectra of liquid samples with J-scaling in inhomogeneous fields via two-dimensional intermolecular multiple-quantum coherence acquisitions. In the resulting one-dimensional projection spectra, apparent J-coupling constants were obtained with a scaling factor theoretically varying from zero (completely decoupled) to infinity relative to the original J-coupling constants while retaining information on chemical shifts, relative peak areas, and multiplet patterns. This allows either an accurate measurement of small J-coupling constants of weakly coupled spin systems or less crowded spectra for spin systems with J-splitting. Experimental observations and simulation results agree with theoretical analysis.
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