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Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cross-reactivity00:42

Cross-reactivity

Overview

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Updated: Jun 22, 2026

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
12:09

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

Published on: May 2, 2011

Vaccination safety update.

Burkhard Schneeweiss1, Michael Pfleiderer, Brigitte Keller-Stanislawski

  • 1Karolinenhofweg 20, Berlin, Germany. schneeburk@gmx.de

Deutsches Arzteblatt International
|May 28, 2009
PubMed
Summary
This summary is machine-generated.

Recent biased reports questioning vaccine safety are unjustified. Modern vaccines undergo rigorous testing and continuous monitoring, ensuring their safety profile is well-established and scientifically supported.

Keywords:
safetyside effectssurveillanceunjustified scepticism about vaccinesvaccination

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Area of Science:

  • Immunology
  • Public Health
  • Pharmacovigilance

Background:

  • Recent media reports, particularly online, have raised concerns about vaccine safety in Germany.
  • This paper addresses the safety profile of contemporary vaccines and their ongoing surveillance.

Purpose of the Study:

  • To critically evaluate the scientific basis of vaccine safety concerns.
  • To differentiate between justified and unjustified reports on vaccine adverse effects.

Main Methods:

  • A selective literature search was conducted.
  • Analysis focused on distinguishing evidence-based reports from unsubstantiated claims regarding vaccine safety.

Main Results:

  • New vaccines require extensive large-scale clinical trials for licensure.
  • Post-licensure, vaccine safety is continuously monitored and findings are published.

Conclusions:

  • Existing data demonstrate that current vaccine safety concerns are not scientifically supported.
  • The safety of modern vaccines is robustly established through pre- and post-licensure evaluations.