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Updated: Jun 22, 2026
05:40
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
Published on: July 29, 2021
[Hydrocortisone treatment and prevent post-dural puncture headache: case reports]
José Francisco Nunes Pereira das Neves1, Vinícius La Rocca Vieira, Rodrigo Machado Saldanha
1CET, SBA, HU, UFJF, Brazil. jfnpneves@terra.com.br
Revista Brasileira De Anestesiologia
|May 28, 2009
Summary
Hydrocortisone effectively treated post-dural puncture headache (PDPH) unresponsive to other methods and prevented it after accidental dural puncture. Further studies are needed to confirm hydrocortisone
Area of Science:
- Anesthesiology
- Neurology
Context:
- Post-dural puncture headache (PDPH) is a common complication following spinal anesthesia or accidental dural perforation.
- Conventional treatments and epidural blood patches (EBP) are not always effective.
Purpose:
- To describe the use of hydrocortisone for treating and preventing PDPH.
- To evaluate hydrocortisone's efficacy in refractory PDPH and after dural perforation.
Summary:
- A case series involving three patients treated with intravenous hydrocortisone.
- One patient with severe PDPH refractory to medication and EBP experienced complete remission.
- Two patients with accidental dural perforation received preventive hydrocortisone and did not develop PDPH.
Impact:
- Hydrocortisone shows potential as an effective treatment for refractory PDPH.
- Preventive hydrocortisone may reduce PDPH incidence in patients with dural perforation.
- Controlled trials are necessary to establish hydrocortisone's definitive role in PDPH management.
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