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[Gastromiro vs gastrografin vs prontobario CAT for computerized tomography. Multicenter study]
G A Rollandi1, P F Curone, C Pastorino
1Tecnomedica Ricerche, Genova.
La Radiologia Medica
|September 1, 1991
Summary
Gastromiro, a new oral non-ionic contrast medium, offers superior small bowel opacification and less diarrhea compared to Gastrografin and Prontobarium-CT for abdominal CT scans.
Area of Science:
- Radiology
- Gastroenterology
- Medical Imaging
Background:
- Intestinal loop opacification is crucial during abdominal CT to differentiate normal anatomy from pathology.
- Standard oral contrast agents include Gastrografin and Prontobarium-CT.
Purpose of the Study:
- To evaluate the efficacy and tolerance of a new non-ionic oral contrast medium, Gastromiro.
- To compare Gastromiro against Gastrografin and Prontobarium-CT for abdominal CT examinations.
Main Methods:
- A comparative study involving 818 consecutive patients undergoing abdominal CT.
- Patients received 500 ml of either Gastromiro (11.1%), Gastrografin (11.1%), or Prontobarium-CT (1.7%) 20 minutes prior to imaging.
- Evaluated parameters included patient tolerance (taste, vomiting), gut opacification quality, and adverse reactions within 24 hours.
Main Results:
- No significant difference in opacification quality for the stomach, duodenum, and large bowel.
- Gastromiro demonstrated significantly higher contrast resolution for small bowel opacification.
- Gastromiro was associated with significantly less diarrhea compared to Gastrografin and Prontobarium-CT.
Conclusions:
- Gastromiro offers superior small bowel opacification and improved patient tolerance due to reduced diarrhea.
- This non-ionic contrast medium presents a viable alternative for abdominal CT, enhancing diagnostic accuracy.