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Published on: July 28, 2020
[Abdominal desmoid tumor: pathologic and therapeutic concepts]
Nadia Kourda1, Sana Ben Slama, Najoua Mrabet
1Service d Anatomie Pathologique, Hôpital Charles Nicolle, Tunis, Tunisie.
La Tunisie Medicale
|May 29, 2009
Summary
Abdominal desmoid tumors are locally aggressive tumors. This study found no local recurrence in three surgically treated cases, suggesting potential for improved outcomes with surgical management.
Area of Science:
- Oncology
- Pathology
Background:
- Abdominal desmoid tumors are locally aggressive neoplasms affecting young adults (20-40 years).
- These tumors exhibit a significant local recurrence rate (20-30%).
Observation:
- A retrospective analysis of three abdominal desmoid tumor cases diagnosed between 1990-2004.
- The cases involved three female patients aged 30, 35, and 62 years, all treated surgically with tumors measuring 5-7 cm.
Findings:
- Immunohistochemical analysis for actin, desmin, CD34, and vimentin was performed.
- CD117 and hormonal receptors were negative in all three cases.
- No local recurrence was observed in any of the patients during the follow-up period.
Implications:
- Abdominal desmoid tumors are locally aggressive but non-metastatic.
- The absence of CD117 and hormonal receptor expression does not preclude response to anti-estrogen therapy.
- Surgical intervention appears to be effective in preventing local recurrence in abdominal desmoid tumors.
