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Updated: Jun 22, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
[Myofibroblastic tumor of the great omentum]
Jamel Ben Achour1, Ibtissem Bouasker, Riadh Bedoui
1Service de Chirurgie Générale Beau Séjour, Hôpital Charles Nicolle, Tunis.
Background:
Myofibroblastic tumors are a spindle cell lesion of indeterminate malignant potential. Abdominal location was rare.
Aim:
We report a case of an unusual location of myofibroblastic tumors in the great omuntum.
Case Report:
A 63-year-old women presented with a one year of isolated left hypochondrium pain. Physical examination was normal. CT scan of the abdomen showed a multicystic and a multilocular building-up of the great omentum suggestive of a peritoneal haemolymphagioma. Besides, at the MRI, this lesion showed up with threefold component: cystic, plump and fibrous, all leading towards a myofibroblastic tumor. At laparotomy, there was already a 10 cm diameter cystic tumor of the great omentum, composed of numerous cystic sockets, all filled with a thick brunish substance. A total resection of the great omentum was done, thus taking away the whole tumor. The histological examination confirms the diagnosis of myofibroblastic tumor of great omentum.. Post operative evolution was uneventful. One year later there were no signs of recurrence.
Conclusion:
Myofibroblastic tumors of the great omentum are rare. The diagnosis is often confirmed by careful microscopic examination or immunohistochemical markers. Treatment consists on a complete surgical resection and life-time follow-up is needed because the risk of recurrence.
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